The Biomedical Imaging and Photonics Society welcomes you attend to the upcoming 'Invited Speaker Series' of our weekly BioPhotonics Journal club.
Our first invited talk is on Friday, April 23, at 4 p.m. over Zoom. The speaker will be Dr. Jonathan Liu, from the University of Washington.
Zoom link to join: https://zoom.us/j/96301904976?pwd=djdPaDRNbjhSWnE4UHEydXNHc1Jjdz09
Title: Nondestructive 3D pathology with open-top light-sheet microscopy for precision medicine.
Abstract: In order to catalyze a digital pathology transformation, a novel technological approach is needed that offers significant advantages over traditional histopathology in terms of accuracy, throughput, comprehensive 3D sampling of specimens, and superior sample preservation (including nucleic acids). We have developed an open-top light-sheet (OTLS) microscopy platform for slide-free 3D pathology of whole biopsies and surgical specimens. Using machine-learning techniques, we are quantifying structural and molecular biomarkers within intact specimens for prognosticating patient outcomes (indolent vs. aggressive disease) and predicting treatment response. These nondestructive large-volume digital pathology methods are synergistic with the growing fields of radiomics and genomics, which collectively have the potential to significantly improve treatment decisions for individual patients, including underserved populations.